t-Butyl 2-bromo-2-methylpropionate
t-Butyl 2-bromo-2-methylpropionate
CAS:
Molecular Formula: C8H15BrO2
t-Butyl 2-bromo-2-methylpropionate - Names and Identifiers
t-Butyl 2-bromo-2-methylpropionate - Physico-chemical Properties
| Molecular Formula | C8H15BrO2 |
| Molar Mass | 223.1075 |
t-Butyl 2-bromo-2-methylpropionate - Introduction
Tert-butyl 2-bromo-2-methylpropionate, also known as tert-Butyl 2-bromomomethylpropanoate, has the chemical formula C8H15BrO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Molecular weight: 227.11g/mol
-Melting point:-61 ° C
-Boiling point: 103-105 ° C
-Solubility: Soluble in ethers, alcohols and organic solvents
Use:
-2-bromo-2-methylpropionic acid tert-butyl ester is an important intermediate in organic synthesis and is commonly used in the synthesis of other organic compounds.
-In the field of medicine, it can be used to synthesize tumor treatment drugs, etc.
-Used as a synthetic raw material for plant growth regulators.
Preparation Method:
The preparation method of 2-bromo-2-methylpropionic acid tert-butyl ester can be carried out by the following steps:
1. Reaction of tert-butyl acrylate with excess HBr to obtain tert-butyl 2-bromopropionate.
2. Under anhydrous conditions, tert-butyl 2-bromopropionate is reacted with a base to obtain tert-butyl 2-bromo-2-methylpropionate.
Safety Information:
-2-Bromo-2-methylpropionic acid tert-butyl ester is generally stable under normal use conditions, but avoid exposure to high temperatures, open flames and strong oxidants.
-May cause irritation when in contact with skin. Wear protective gloves and glasses.
-Avoid inhalation or ingestion, and maintain good ventilation during use.
-If inhaled or touched, rinse immediately with water and seek medical help.
Nature:
-Appearance: colorless liquid
-Molecular weight: 227.11g/mol
-Melting point:-61 ° C
-Boiling point: 103-105 ° C
-Solubility: Soluble in ethers, alcohols and organic solvents
Use:
-2-bromo-2-methylpropionic acid tert-butyl ester is an important intermediate in organic synthesis and is commonly used in the synthesis of other organic compounds.
-In the field of medicine, it can be used to synthesize tumor treatment drugs, etc.
-Used as a synthetic raw material for plant growth regulators.
Preparation Method:
The preparation method of 2-bromo-2-methylpropionic acid tert-butyl ester can be carried out by the following steps:
1. Reaction of tert-butyl acrylate with excess HBr to obtain tert-butyl 2-bromopropionate.
2. Under anhydrous conditions, tert-butyl 2-bromopropionate is reacted with a base to obtain tert-butyl 2-bromo-2-methylpropionate.
Safety Information:
-2-Bromo-2-methylpropionic acid tert-butyl ester is generally stable under normal use conditions, but avoid exposure to high temperatures, open flames and strong oxidants.
-May cause irritation when in contact with skin. Wear protective gloves and glasses.
-Avoid inhalation or ingestion, and maintain good ventilation during use.
-If inhaled or touched, rinse immediately with water and seek medical help.
Last Update：2024-04-09 15:17:46
